摘要
目的:研究学龄前儿童原发垂体性生长激素缺乏症垂体的MRI特征。方法:回顾分析46例原发垂体性生长激素缺乏症儿童(病例组)垂体的MR影像特征,并与35例同龄健康儿童(对照组)作对照比较。结果:病例组腺垂体平均高度(2.32±0.78)mm,与脑干对比,34例T1WI信号低于脑干,12例信号与脑干相等;44例垂体柄完整连续,矢状面平均宽径(0.89±0.51)mm;2例垂体柄缺如;2例垂体后叶异位于下丘脑漏斗底部的正中隆起。4例合并中枢神经系统畸形。对照组腺垂体高度、垂体柄宽径分别为(3.76±1.21)mm、(1.64±0.59)mm。病例组腺垂体高度、垂体柄矢状宽径均比正常对照组小,差异具有显著性意义。结论:MRI能够清楚的显示原发垂体性生长激素缺乏症垂体的影像学特征,表现为垂体前叶变小,信号低于或等于脑干,垂体柄变细或缺如,大多数垂体后叶位置正常,少数病例后叶异位,以及合并的中枢神经系统畸形。
Objective:To describe the MR characteristics in preschool children with idiopathic pituitary growth hormone deficiency (IPGHD).Methods:MR images of 46 preschool-age children with IPGHD (study group) were reviewed retrospectively.The MR findings of the study group were compared with those of 35 healthy children at the same age (control group).Results:In the study group,the height of pituitary gland was (2.32±0.78)mm.The signal intensity of adenohypophysis was isointense to brainstem in 12 cases and hypointense in 34 cases on the T1-weighted images.The pituitary stalks were complete and continuous in 44 patients,the width of which were (0.89±0.51)mm on sagittal images and absent in two patients.The posterior pituitary was ectopic in 2 cases.Four patients were found to have midline central nervous system malformations.The height of pituitary gland and the width of pituitary stalks were (3.76±1.21)mm and (1.64±0.59)mm respectively in the control group,the difference of which were statistically significant (P0.05) compared with the study group.Conclusion:MR imaging can clearly show the pituitary abnormalities in patients with IPGHD,including a small and hypointensive signal of anterior pituitary lobe to brainstem,a small or absent pituitary stalk,an ectopic posterior pituitary and central nervous system malformation.
出处
《放射学实践》
北大核心
2010年第10期1090-1093,共4页
Radiologic Practice
关键词
人生长激素
侏儒症
垂体性
垂体
磁共振成像
儿童
学龄前
Human growth hormone
Dwarfism
pituitary
Pituitary gland
Magnetic resonance imaging
Child
preschool