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椎动脉硬化形态学特点及其临床表现

Study on Clinical and Morphologic Characteristics of Vertebral Atherosclerosis
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摘要 目的:观察椎动脉硬化形态学变化特点,以及椎动脉形态变化与临床表现的关系.方法:对415例患者行全脑数字减影血管造影检查.结合临床表现对椎动脉的形态变化(迂曲延长和狭窄)进行分析.结果:415例中,造影显示椎动脉迂曲延长和狭窄311例(74.9%),其中迂曲延长者176例(56.6%)、动脉狭窄者135例(43.4%);在动脉迂曲延长中,"C"型、"S"型和"O"型迂曲分别为54.5%(96/176)、32.4%(57/176)和13.1%(23/176)."C"型迂曲表现为头昏者占54.2%(52/96),高于"S"型的28.1%(16/57)和"O"型的17.4%(4/23),组间比较差异有统计学意义(P<0.05).而脑梗塞发生率"C"型与另两型比较,差异无统计学意义(P>0.05).结论:椎动脉硬化形态学变化越明显,临床表现越严重.椎动脉硬化形态变化的原因有待于进一步研究. Objective:To observe the morphologic changing characteristics and clinical manifestations of vertebral artery stenosis. Methods:415 patients underwent digital subtraction angiography(DSA) , the mor- phologic changes of vertebral artery combined with the clinical manifestations were analyzed( circuity extension and stenosis ). Results:311 cases(74.9% ) of DSA with circuity extension or stenosis in 415cases, of which circuity extension in 176 cases (56.6%), stenosis in 135 cases (43.4%) . There were 96 cases (54.5%) with"C" type and 57 cases (32.4%) with "S" type and 23 cases (13.1%) with "O" type. There were 54.2% (52/96) ,28.1% (16/57) and 17.4% (4/23) with dizziness in " C" ," S" and " O" typed tortuosity. There was a significant difference between the " C" and "S" typed tortuosity(P 〈 0.01 ) and between the " C" and "O" typed tortuosity (P 〈 0.05 ). The "S" type and "0" type induced cerebral infarction were not significant difference than the " C" type( P 〉 0.05). Conclusions:The morphologic changing characteristics of vertebral artery obviously affect its clinical manifestations and the causes need further study.
作者 易旭 周华东
出处 《解剖与临床》 2010年第5期307-310,共4页 Anatomy and Clinics
关键词 椎动脉 解剖变异 数字减影血管造影 迂曲延长 危险因素 Vertebral artery Anatomic variation Digital subtraction angiography Circuity and extension Risk factors
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