摘要
目的:观察中西医结合治疗高血压早期肾功能损害的疗效。方法:将60例高血压病早期肾功能损害患者随机分为治疗组和对照组,各30例。对照组常规西药治疗,治疗组在对照组的基础上加用中药丹黄降氮汤口服,观察临床症状及肾功能变化。结果:治疗组总有效率93.3%,对照组总有效率66.7%,两组比较差异有统计学意义(P<0.05)。治疗组治疗后肾功能血BUN、Sur下降明显,与对照组比较差异有统计学意义(P<0.05)。结论:中西医结合治疗高血压病早期肾功能损害疗效优于常规西药治疗,其作用机制可能为提高肾血流量、增加毒素排泄,从而改善肾功能,延缓肾衰病程发展。
Objective:To observe the effects of Danhuangjiangtan decoction as adjuvant therapy on early renal dysfunction in patients with hypertension.Methods:A total of 60 patients with hypertension were randomized into a control group and Danhuangjiangtan decoction group,30 in each.The control group were treated with conventional western drugs and Danhuangjiangtan decoction was added to western drug therapy in the other group.Signs and symptoms and renal function were observed before and after treatment.Results:The curative rate was was 93.3% in the Danhuangjiangtan decoction group and 66.7% in the control group(P〉0.05).Serum BUN and Sur in the Danhuangjiangtan decoction group was reduced more than those in the control group(P〈0.05).Conclusion:Danhuangjiangtan decoction may add the effect to improve the early renal function in hypertension patients by increasing blood flow and toxin excretion on the basis of conventional western drug therapy.
出处
《浙江中西医结合杂志》
2010年第11期663-665,共3页
Zhejiang Journal of Integrated Traditional Chinese and Western Medicine
关键词
高血压病
早期肾功能损害
中西医结合疗法
丹黄降氮汤
hypertension early renal dysfunction integrated Chinese and western therapy Danhuangjiangtan decoction