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泌尿生殖道支原体感染临床耐药性分析

Analysis of Clinical Drug Resistance of Mycoplasma in the Genitourinary Tract Infection Patients
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摘要 目的:比较抗生素对泌尿生殖道抗菌作用,为临床合理用药提供依据。方法:对诊断为宫颈炎、阴道炎和非淋菌性尿道炎的1183例患者的宫颈或尿道分泌物进行支原体培养-药敏一步法培养检测分型并分析其耐药性。结果:解脲支原体(Uu)356例,人型支原体(Mh)16例,Uu和Mh混合感染162例,合计534例;女性352例(65.9%),男性182例(34.1%),女性明显高于男性(P<0.01)。9种抗生素中Uu和Mh对米诺环素、多西环素和交沙霉素敏感性强,Uu合并Mh感染对抗菌药物的耐药率明显增高。结论:治疗泌尿生殖道支原体感染应根据药敏试验结果来选用抗生素。 Objective: To provide information for the clinical application by comparison of antibacterial action of antibiotics in the genitourinary tract infection patients. Methods: Cervix or urethral secretions were obtained from 1183 patients with cervicitis, vaginitis or nongonococca] urethritis. The mycoplasma detection was achieved by culture-susceptibility test. Results: Amount to 534 cases were infected with mycoplasma including 352 female (65.9%) and 182 male (34.1%) male, among which, 356 cases were mycoplasma urealytium (Uu), 16 cases were human mycoplasma (Mh) and 162 cases were combined infection. The female have higher infection rate than the male (P〈0.01), Uu and Mh were sensitive to minocycline, deoxycycline and josamycin. The combined infection exhibited highly resistant to antibacterials. Conclusions: Antibiotics for genitourinary tract mycoplasma infection should be selected according to the result of drug susceptibity test.
出处 《药学与临床研究》 2010年第5期449-451,共3页 Pharmaceutical and Clinical Research
关键词 泌尿生殖道感染 解脲支原体 人型支原体 耐药性 Genitourinary tract infection Mycoplasma urealytiurn Human type mycoplasma Drug resistance
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