摘要
目的:研究2型糖尿病患者心律失常发生状况及其相关危险因素。方法:回顾分析239例住院2型糖尿病患者,根据常规心电图检测有无心律失常,分为心律失常组66例,无心律失常组173例,对2组患者的相关临床资料、心电图检查结果进行分析比较。结果:心律失常发生率为27.6%,以房性期前收缩最多见;2型糖尿病伴高血压、冠心病更易发生心律失常(P<0.01或P<0.05);心律失常组的年龄、体重、体质指数、糖尿病病程、高血压病程、冠心病病程、收缩压、空腹胰岛素、LDL-C、胰岛素抵抗指数高于无心律失常组(P<0.01或P<0.05);logistic回归分析显示:年龄、糖尿病病程、高血压病程、疾病种类为发生心律失常的相关危险因素。结论:2型糖尿病患者伴其他心血管疾病更易发生心律失常,可能与疾病病程长、胰岛素抵抗程度重、伴其他疾病而造成心脏血管、心肌、神经病变有关。
Objective：To explore the characteristics of arrhythmia in patients with type 2 diabetes mellitus and the related risk factors. Method：According to arrhytbmia detection of routine ECG, 239 hospitalized patients with type 2 diabetes mellitus were divided into two groups, 66 cases of arrhythmia group, 173 cases of non-arrhythmia group. The clinical data and ECG results of two groups were analyzed and compared. Method：According to arrhythmia detection of routine ECG, 239 hospitalized patients with type 2 diabetes mellitus were divided into two groups： 66 cases of arrhythmia group and 173 cases of non arrhythmia group. The clinical data and ECG results of two groups were analyzed and compared. Result：The incidence rate of arrhythmia in 239 patients with type 2 diabetes was 27.6%, and the most common type was atrial premature beats. Type 2 diabetes with hypertension and （or） coronary heart disease more easily leaded to increase of arrhythmia （P〈0.01 or P〈0.05）. Age, weight, body mass index （BMI）, diabetes duration, hypertension duration, coronary heart disease duration, systolic blood pressure, fasting insulin （FINS）, low density lipoprotein cholesterol （LDL-C） and insulin resistance index （HO- MA-IR） in arrhythmia group were higher than in non-arrhythmia group（P〈0.01 or P〈0.05）. Logistic regres- sion analysis showed： age, diabetes duration, hypertension duration and type of diseases are predisposed risk factors for arrhythmia. Conclusion：Type 2 diabetes mellitus with other cardiovascular diseases is more likely to occur arrhythmia. It is probably related to pathological changes of cardiovascular, myocardium and autonomic nervous caused by long diseases durations, serious insulin resistance and othhr diseases.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2010年第10期726-729,共4页
Journal of Clinical Cardiology
关键词
心律失常
2型糖尿病
高血压病
冠心病
胰岛素抵抗
arrhythmia
type 2 diabetes mellitus
hypertension
coronary heart disease
insulin resistance
