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不同rag基因型牙龈卟啉单胞菌在战士牙龈炎中的分布及牙周病风险研究

Study: Distribution of rag genotypes of Porphyromonas gingivalis and the risk of periodontal disease
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摘要 目的 调查某武警部队战士牙龈健康情况,并分析不同rag基因型牙龈卟啉单胞菌在牙龈炎患者中的分布以及牙周病发病风险.方法 武警某部队158名战士进行牙周疾病调查,统计牙龈炎和牙结石的发病率.通过PCR检查rag-1、2、3、4在牙龈炎中的分布,并统计在轻度牙龈炎和中重度牙龈炎组中的分布差异性.结果 牙龈炎检出率为65.2%,牙结石检出率为74.1%.病变位点牙龈卟啉单胞菌阳性检出率为68.5%.rag-1为64.3%,rag-2为24.5%,rag-3为54.1%,rag-4为17.3%.rag-1和rag-3型检出率较高(均P〈0.05).而在牙龈炎重度组中rag-1的检出率最高(P〈0.01).结论 牙龈炎和牙结石具有非常高的检出率,同时Rag-1的高检出率提示牙周病的高风险,应对武警部队战士牙周病的防治给予高度的重视. Objective To investigate gingival disease incidence of the People's Armed Police Forces soldiers and the distribution of rag genotypes of Porphyromonas gingivalis (P.gingivalis) in gingivitis. Methods Investigate the disease incidence of gingivitis and odontolith among the 158 soldiers. Distribution of rag genotypes was assessed in P. gingivalis positive samples by PCR. Results The result was showed the incidence of gingivalis 65.2%, the odontolith 74.1%, and occurrence of P.gingivalis 68.5%. The distribution of four rag genotypes among P.gingivalis positive sampleswas was shown as follows: rag-1 64.3%, rag-2 24.5%, rag-3 54.1%, and rag-4 17.3%, respectively. Occurrence of rag-1 and 3 was reflected typical from statistical perspective, predominant in moderately-severely gingivitis. Conclusion The result from those examined soldiers reflected the high occurance of gingivalis and odontolith. P.gingivalis with rag-1 was more predominant in gingivalis patients which indicated a greater chance to cause periodontitis. The research suggested that safeguard of oral health for the army should be improved.
出处 《中国急救复苏与灾害医学杂志》 2010年第10期914-916,共3页 China Journal of Emergency Resuscitation and Disaster Medicine
基金 武警总部课题(WZ2009001)
关键词 牙龈卟啉单胞菌 基因型 rag基因 Porphyromonas gingivalis Genotype Rag gene
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