摘要
生理药动学模型是一种模拟机体循环系统的血液流向,将各器官或组织相互联结起来而建立的整体模型,能够准确描述兽药在动物可食性组织的残留消除规律,并可预测休药期。就生理药动学模型及在兽药残留分析中的应用进行综述。
Physiologically based pharmacokinetic model was a whole model which was developed by connecting each organ or tissue according to the blood flow.It could exactly describe residue depletion of veterinary drugs in animal edible tissues,and predict residue withdrawal times.Physiologically based pharmacokinetic model and application in the analysis of residues of veterinary drugs were introduced in the article.
出处
《广东农业科学》
CAS
CSCD
北大核心
2010年第10期44-47,共4页
Guangdong Agricultural Sciences
基金
国家"十一五"科技支撑计划项目(2006BAD31B01)
广东省农业科技重大专项(2007B080401018
2008A080401008)
关键词
兽药残留
残留消除规律
休药期
生理药动学模型
veterinary drug residues
residue depletion
withdrawal times
physiologically based pharmacokinetic model
