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膀胱ICCs细胞SCF/c-kit信号通路研究现状 被引量:3

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摘要 膀胱ICCs细胞是Smet和Jonavicius等于1996年首先在豚鼠和人逼尿肌发现的类似于胃肠道Cajal间质细胞(In-terstitial cells of Cajal,ICC)的一种特殊间质细胞。它是泌尿系平滑肌蠕动的起搏者,在膀胱逼尿肌兴奋收缩过程中起着重要作用。最新研究表明SCF/c-kit通路与ICCs细胞形态和功能的维持密不可分,信号通路的异常会导致ICCs表型和功能的转变,这一发现为之后的尿动力方面研究提供了新的平台。
出处 《中国现代医药杂志》 2010年第10期124-126,共3页 Modern Medicine Journal of China
基金 2009年国家自然科学基金(编号:30860281)
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