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脑卒中偏瘫痉挛中替扎尼定的疗效观察 被引量:7

Application of tizanidine in treatment of spastic hemiplegia of stroke
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摘要 目的:观察脑卒中偏瘫肌痉挛患者使用替扎尼定治疗的效果。方法:将42例脑卒中所致偏瘫患者随机分为治疗组21例和对照组21例。入院后均接受同样的神经内科常规药物治疗以及康复训练。其中对照组在上述治疗的基础上采用口服替扎尼定治疗。采用改良的Ashworth分级法(modified Ashworth scores,MAS)对两组患者治疗前后肌张力进行评定。结果:经过治疗,两组患者肌张力较治疗前均有明显降低(P<0.005),且治疗组疗效明显优于对照组(P<0.005)。结论:替扎尼定对脑卒中所致偏瘫肌痉挛有显著的改善作用。 Objective:To observe the efficacy of tizanidine in the treatment of spastic hemiplegia of stroke.Methods:42 hemiplegic patients after stroke were divided randomly into treatment group (21 cases) and control group (21 cases).All patients received the same neurological routine medication and rehabilitation.In addition,the treatment group also received oral administration of tizanidine.Muscular tension was measured with modified Ashworth scores (MAS) before and after the treatment.Results:Muscular tension in both groups was decreased after the treatment(P0.005).The efficacy of the treatment group was better than that of the control group(P0.005).Conclusion: Tizanidine could significantly improve spastic hemiplegia caused by stroke.
出处 《现代医药卫生》 2010年第22期3389-3390,共2页 Journal of Modern Medicine & Health
关键词 脑卒中 肌痉挛 替扎尼定 Stroke Myospasm Tizanidine
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