摘要
目的探讨近十年来随着内镜、药物和认识的提高,肝性脑病(HE)的发病学改变及其原因。方法按食道静脉曲张破裂出血的药物和内镜下止血以及HE治疗药物的进展情况,把1989~1997.9分为1989~1992.12;1993.1~1996.12和1997.10~1997.9三个年度,分析发病率、病情程度、死亡率和死因等因素的变化。结果尽管HE的发病率逐年增加,但其严重程度和死于上消化道出血的患者却逐年下降,合并肝功能衰竭和肝肾综合征成为主要死亡原因。结论随药物和内镜技术的发展,HE的发病学发生了明显变化,患者预后明显好转。
Objective To stu8y the changes of prevalence 0f hepatic encephalopathy (HE) inabout ten years and its causes. Methods According to the developments in the drug and end0scopictherapy of esophageal-gastric variceal bleeding as well as in the drug treatment of HE, we divided theperiod (1989-9, 1997) into three peri0ds: 1989-12' 1992 1 , 1993-12, 1996 and 1, 1997-9, 1997, and we in-vestigated the incidence, severity, m0rtality of HE patients and its causes. Results Although the inci-dence of HE increased year by year in this ten years, its severity and mortality from variceal bleeding de-creased steadily. Therefore, hepatic failure and hepatorenal syndrome became the main causes for thedeath of HE patients. Couclusiou With the developments in the drug and endoscopic therapy, greatchanges has taken place in the prevalence of HE and the patient's prognosis has been greatly improved.
出处
《中国全科医学》
CAS
CSCD
1999年第3期188-189,共2页
Chinese General Practice
关键词
肝性脑病
发病率
死亡率
流行病学
Hepatic encephalopathy Incidence Mortality Prevalence