摘要
目的 探讨在急诊中应用双水平正压通气（BiPAP）呼吸机治疗慢性阻塞性肺疾病加重期（AECOPD）合并Ⅱ型呼吸衰竭患者的临床疗效.方法 52例AECOPD合并Ⅱ型呼吸衰竭的患者随机分成常规治疗组和常规治疗加BiPAP组.对照组（26例）给予常规抗感染,通畅气道,持续低流量吸氧及应用呼吸兴奋剂等治疗.试验组（26例）则在常规治疗基础上予BiPAP无创通气治疗.结果 经BiPAP呼吸机治疗组的临床症状改善和血气分析指标、肺功能恢复正常,与常规治疗的对照组比较差异有统计学意义（P〈0.05）.结论 急诊中应用BiPAP呼吸机治疗AECOPD合并Ⅱ型呼吸衰竭可以明显缓解临床症状,提高动脉血气分析及肺功能.试验组较对照组pH、PaO2、PaCO2、肺功能第一秒用力呼气容积（FEV1）、用力肺活量（FVC）、第一秒用力呼气容积/用力肺活量（FEV1/FVC）和第一秒用力呼气容积占预计值百分比（FEV1%）等明显改善,是一种有效手段.
Objective To investigate the therapeutical effect of the bi-level positive airway pressure（BiPAP） ventilator in the emergency treatment of chronic obstructive pulmonary disease（COPD）with type Ⅱ respiratory failure.Methords 52 patients with acute exacerbation of COPD combined with type Ⅱ respiratory failure were divided into conventional treatment group,conventional methods and plus BiPAP noninvasive ventilation group randomly.The contrast group （ 26 cases ） was given conventional anti-infection,medication,using clean airway, and inhaling low concentration oxygen continuously and pneumatic analeptic.The experimental group（26 cases） was treated with traditional methods and plus BiPAP noninvasive ventilation.Results The bi-level noninvasive positive pressure ventilator-assisted ventilation in the treatment group to improve the clinical symptoms, blood gas analysis indicator and lung function returned to normal,and the difference between the experimental group and the contrast group was significant（P 〈 0.05）.Conclusion Application of BiPAP ventilator in emergency treatment of acute exacerbation of chronic obstructive pulmonary diseases with type Ⅱ respiratory failure improved the clinical symptoms,blood gas analysis indicator and lung function significantly.pH,PaO2,PaCO2,FEVI,FVC,FEVI/FVC and FEVI% were superior in experimental group to control group.It was an effective method.
出处
《中国血液流变学杂志》
CAS
2010年第3期414-416,共3页
Chinese Journal of Hemorheology
