摘要
血管性认知功能损害(VCI)是指由血管因素导致或与之伴随的认知功能损害,除卒中外,血管性脑的损害及高血压、糖尿病、冠心病等血管性危险因素也是重要原因。VCI是异质性的临床状态,涵盖了从轻微认知损害到血管性痴呆的各种表现,皮质下缺血性小血管病是其中最常见的类型,以执行功能受损和伴发淡漠、抑郁障碍为特征。对VCI的诊断主要依据临床表现并参考各自不同的表现类型。应按照临床证据和指南要求规范进行治疗干预。
Vascular cognitive impairment indicates the cognitive impairment caused by or associated with vascular factors such as stroke, vascular brain lesions, hypertension, diabetes, and coronary heart disease, etc. Vascular cognitive impairments contain a heterogenous group of clinical conditions from subtle cognitive changes to definite vascular dementia. Subcortical ischemic vascular disease is the most common cause of VCI and clinically characterized by executive dysfunction, apathy, and depression. The diagnosis process of VCI is mainly clinicalbased and should be individualized according to the manifestations. The therapeutic intervention of VCI should be evidencebased with observations to guidelines.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2010年第10期891-894,共4页
Chinese Journal of Practical Internal Medicine
