摘要
目的评价在青少年肥胖女性中血清睾酮水平与代谢综合征的关系。方法 96例女性纳入本实验,年龄10～17岁,体重指数(29.5±4.7)kg/m2。分别检测其血清睾酮,及代谢综合征的指标(血压、腰围、血脂、空腹胰岛素、OGTT、HOMA-IR指数)。结果血清睾酮水平与收缩压、舒张压、腰围、甘油三酯、高密度脂蛋白胆固醇、空腹胰岛素、2小时血糖和HOMA-IR指数具有明显的相关性。其中代谢综合征患者和非代谢综合征者的血清睾酮水平差异有统计学意义(P<0.05)。结论青少年肥胖女性中血清睾酮水平与代谢综合征具有明显相关性。
Objective To evaluate the relationship between serum testosterone concentration and metabolic syndrome in obese adolescent girls.Methods In 96 obese adolescent girls（aged 10-17 years,mean BMI 29.5±4.7 kg/m2）,serum testosterone,and components of metabolic syndrome（blood pressure,waist circumference,serum lipids,fasting insulin,oral glucose tolerance test and HOMA-IR index） was measured.Results Serum testosterone concentration correlated signifi cantly to systolic blood pressure,diastolic blood pressure,waist circumference,triglycerides,high-density lipoprotein cholesterol,fasting insulin,2 hours glucose,and HOMA-IR index.Serum testosterone concentrations in obese adolescent girls with and without metabolic syndrome are signifi cantly different（P0.05）.Conclusion Serum testosterone was signifi cantly related with metabolic syndrome in obese adolescent girls.
出处
《当代医学》
2010年第26期63-64,共2页
Contemporary Medicine
关键词
睾酮
代谢综合征
青少年肥胖女性
胰岛素抵抗
testosterone
metabolic syndrome
obese adolescent girls
insulin resistance
