摘要
【目的】分析龈沟液中骨粘连蛋白的含量变化规律,探讨其与牙周炎活动性的关系。【方法】选择本院2008年5月-2009年1月慢性牙周炎患者40例,其中静止期组20例,活动期组20例,采用酶联免疫吸附试验检测两组患牙龈沟液中骨粘连蛋白的含量。【结果】活动期组龈沟液中骨粘连蛋白的浓度为(3.46±0.91)ng/μl,高于静止期组骨粘连蛋白的浓度(2.15±0.72)ng/μl,且差异具有统计学意义(P<0.05)。【结论】龈沟液中骨粘连蛋白的水平变化与牙周组织病变发展密切相关,龈沟液中骨粘连蛋白的水平有可能成为判断牙周炎活动期的参考指标。
【Objective】 To analyze the relationship between osteonectin（ON） levels in gingival crevicular fluid（GCF） and the activity of periodontitis.【Methods】 Forty patients were equally divided into two groups： active and non-active groups.The concentration of ON in GCF was measured by enzyme-linked immunosorbent assay（ELISA）.【Results】 Significant difference was found in the concentration of ON in GCF between the active group（3.46±0.91） ng/μl and the non-active group（2.15±0.72） ng/μl（P 0.05）.【Conclusion】 The level of ON in GCF is related to the degree of the progression of periodontal disease.It may be a useful indicator for the activity of periodontitis.
出处
《武警医学院学报》
CAS
2010年第10期780-782,共3页
Acta Academiae Medicinae CPAPF
关键词
骨粘连蛋白
牙周炎
活动性
龈沟液
Osteonectin
Periodontitis
Activity
Gingival crevicular fluid
