摘要
目的和方法:利用改良的MTT比色法测定CTLL2细胞增殖程度而确定IL-15水平的方法,测定了27例支气管哮喘急性发作期病人和40例健康人外周血单核/巨噬细胞培养上清中IL-15的分泌水平。结果:无论刺激与否,哮喘病人IL-15水平均高于健康对照组,两组差异显著(P<005)。
AIM and METHODS:
Interleukin (IL-15) is a newly described cytokine with an action similar to that of IL-2. In this
study, the levels of IL-15 in the supernatants of LPS-stimulated (or not)
monocytes/macrophages were examined in 27 patients with bronchial ashma at acute phase,
and were compared with healthy controls. RESULTS:Signifcant elevation of IL-15 was observed
in supernatants of monocytes/macrophages from patients with asthma as compared with that in
normal individuals, whether LPS existed or not.CONCLUSION:IL-15 plays a role in asthma.
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
1999年第7期626-627,共2页
Chinese Journal of Pathophysiology