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Y型分叉冠状动脉血管中血液流动对血栓形成的影响 被引量:4

Influence of Blood Flow on Thrombosis in Y-Bifurcation Coronary Arteries
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摘要 为研究Y型分叉血管中血液流动对血栓形成的影响,根据黏性流体稳定流动的Navier-Stokes方程,建立了冠状动脉分叉血管中血液流动的数学模型,并采用计算流体力学(computational fluid dynamics,CFD)的方法,数值模拟了不同Y型分叉冠状动脉血管中血液流动情况,并考虑了分叉角度、血液黏度、入口血流初始速度对血流速度场、壁面剪应力、壁面压强的影响.结果表明:分叉角度越小成栓可能性越大,存在最易成栓的血流速度,但血液黏度对血柱形成的影响不大. In order to research blood flow in Y-bifurcation influence on thrombosis, a blood flow model in the Y-Bifurcation coronary arteries is set up based on Navier-Stokes flow of the viscous steady fluid. Blood flow in the difficult Y-Bifurcation coronary arteries is numerically simulated and influences of angle of bifurcation, blood viscidity and initial blood velocity of inlet on velocity field of blood flow, shear stress and pressure on the wall as well as the formation of thrombosis are also investigated by making use of computational fluid dynamics (CFD) method. It is shown from the results that locations apt to thrombus or the best locations to pathological change are in the crotch of Y-Bifurcation. Some guesses of thrombosis formation in medicine research are also proved by the results in the paper.
出处 《北京工业大学学报》 EI CAS CSCD 北大核心 2010年第9期1153-1158,共6页 Journal of Beijing University of Technology
基金 国家自然科学基金资助项目(10502002) 北京市人事局留学回国人员择优资助项目 教育部留学归国基金资助项目 北京市人才强教计划--青年骨干教授项目资助
关键词 分叉血管 血液黏度 壁面压强 壁面剪应力 bifurcation coronary arteries blood viscosity wall pressure wall shear stress
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