摘要
目的研究腹腔镜联合不同药物治疗中重度卵巢子宫内膜异位症患者的复发因素。方法收集116例Ⅱ～Ⅳ期子宫内膜异位症患者行腹腔镜下卵巢子宫内膜异位囊肿剔除术。术后根据用药情况分为三组:A组:55例,术后诺雷德治疗3～6个月,B组31例,术后用孕三烯酮3～6个月,C组30例,术后未用任何药物。比较三组术后复发率并用Logistic回归法分析与复发可能的相关因素。结果总复发率为30.2%。三组复发率差异具有显著性,A组复发率最低(P<0.05)。既往子宫内膜异位的药物治疗、最大囊肿直径和r-AFS高评分与复发有统计学相关,术后药物治疗(诺雷得)和术后妊娠与低复发率相关,而年龄,不孕,疼痛,子宫肌瘤,子宫腺肌病,既往卵巢子宫内膜异位的手术治疗,多发囊肿,双侧或单侧卵巢受累以及是否同时存在深部子宫内膜异位与复发无关。结论中重度的子宫内膜异位症患者腹腔镜保守性手术术后加用诺雷德治疗以及术后妊娠对降低复发率有重要作用。
【Objective】To identify prognostic factors for endometrioma recurrence after complete laparoscopic excision of endometriosis combined with medical treatment. 【Methods】116 patients after complete laparoscopic were collected and divided into three groups of different medicines after surgery. Logistic regression analysis was used to assess the factors on recurrence. 【Results】The overall rate of recurrence was 30.2%. There was a significantly difference among three groups （P 0.05）,and the recurrence of group A was the lowest. Previous medical treatment,larger diameter of the largest cyst and revised r-AFS score were independently associated with higher recurrence. Post-operative pregnancy and medical treatment were protective effects. 【Conclusion】Pregnancy and GnRH-α drugs have a protective effect on disease recurrence,and GnRH-α with lower recurrence than others.
出处
《中国内镜杂志》
CSCD
北大核心
2010年第8期813-816,共4页
China Journal of Endoscopy
