摘要
目的评价喘可治注射液穴位注射治疗中晚期肺癌合并慢性阻塞性肺气肿的疗效。方法选择我院肿瘤科40例中晚期肺癌合并慢性阻塞性肺气肿患者,随机分为两组,视病情需要两组患者均给予吸氧、应用抗生素、纠正电解质紊乱等治疗,疗程14d。治疗组患者加用喘可治注射液穴位注射肺俞(双)、足三里(双),每穴1ml,1次/d,疗程14d;比较两组患者治疗后中医症状缓解率以及肺功能、免疫功能及安全性有无差异。结果两组患者治疗后咳嗽、乏力及气促的缓解率比较,差异均有统计学意义(P<0.05),两组患者治疗后1s用力呼吸容积用力肺活量比值(FEV1%)比较,差异有统计学意义(P<0.05)。喘可治组患者治疗后CD3、CD4升高,CD8下降(P<0.05),CD4/CD8比值升高(P<0.01),CD19升高(P<0.05),与对照组患者比较,差异均有统计学意义(P<0.05)。治疗后两组患者血常规、肝、肾功能及心电图无明显异常。结论喘可治注射液穴位注射治疗中晚期肺癌合并慢性阻塞性肺气肿在改善患者临床症状,提高肺功能及免疫功能方面有较好疗效,且安全性好,值得临床推广。
Objective To evaluate the effect of Chuankezhi point injection treatment on patients of advanced lung cancer with chronic obstructive pulmonary emphysema.Methods 40 patients with advanced lung cancer with chronic obstructive pulmonary emphysema were randomly divided into two groups,patients in the case group were treated with Chuankezhi point injection at Feishu (double),Zu San Li (double),Meixue 1ml,1 times/d,treatment 14 d;According to the condition of patients,both groups were given oxygen,antibiotics to correct electrolyte disorders and the treatment course was 14 d.Clinical symptoms were observed after treatment.The difference in remission rate,lung function changes,immune function and safety was analyzed.Results After treatment,in the clinical symptoms including cough,fatigue and shortness of breath and the remission rate,the difference was significant (P<0.05).After treatment,the difference in 1S breathe volume (FEV1) forced vital capacity ratio of occupied (FEV1/FVC) was significant (P<0.05).Immune function:After treatment the count of CD3 and CD4 cells was significantly higher in the treated group(P<0.05),while the count of CD8 declined and CD4/CD8 ratio increased(P<0.01),the count of CD19 alsoincreased (P<0.05).After treatment the patients′ blood hemogram,liver,renal function and ECG went back to normal.Conclusion Chuankezhi point injection treatment on advanced lung cancer with COPD in improving clinical symptoms,lung function and immune function has good effect and reliable safety,it is worthy of promotion.
出处
《中国全科医学》
CAS
CSCD
北大核心
2010年第21期2397-2399,共3页
Chinese General Practice
关键词
肺肿瘤
肺疾病
慢性阻塞性
肺气肿
喘可治注射液
穴位注射
Lung cancer
Ppulmonary disease
Chronic obstructive
Emphysema
Chuankezhi injection
Point injection
