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Skp2在恶性肿瘤中的研究进展 被引量:2

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摘要 Skp2是泛素连接酶复合物的底物识别蛋白,通过泛素蛋白酶体途径降解p27、p21、p130等多种细胞周期调节因子,在多数恶性肿瘤中表达增高。研究发现Skp2与肿瘤的发生发展、预后、治疗密切相关。现就Skp2结构、功能与肿瘤研究进展作一综述。
作者 姜剑婷
出处 《医学信息》 2010年第20期3935-3936,共2页 Journal of Medical Information
关键词 SKP2 肿瘤 预后
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参考文献8

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