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血清抗Clq抗体对狼疮肾炎病理的预测价值 被引量:1

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摘要 狼疮肾炎(LN)导致肾衰竭是系统性红斑狼疮(SLE)患者死亡的主要原因之一。肾脏病理分型是指导LN治疗的有效方法,但部分患者因各种原因而小能进行肾脏活检。寻找一种实用、便捷的检查手段作为。肾脏病理诊断的一种间接指标具有重要的临床实用价值。抗Clq抗体是LN患者血清中最常见的自身抗体之一,其参与了LN的免疫病理的发生和发展,并与LN疾病活动性和复发相关。本研究对抗Clq抗体在LN疾病活动与肾脏病理分型中的价值进行了探讨,以期明确其在LN中的病理机制及其与肾脏病理的关系。
出处 《中华肾脏病杂志》 CAS CSCD 北大核心 2010年第8期642-643,共2页 Chinese Journal of Nephrology
基金 国家“十一五”科技支撑计划项目(2008BAI59B02) 安徽省自然科学基金(090413129) 安徽省教育厅自然科学研究项目(KJ20098072)
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