摘要
目的:探讨血清总IgE水平和外周血嗜酸性粒细胞计数(EOS)在儿童特应性皮炎(AD)中的临床意义。方法:分别测定轻、中、重度特应性皮炎患儿及同期我院体检的正常儿童各45例血清总IgE水平及外周血嗜酸性粒细胞计数。结果:①特应性皮炎患儿血清总IgE水平为(1026.73±379.25)kU/L,显著高于正常对照组(11.47±2.11)kU/L(P<0.05),而轻、中、重不同严重程度的AD患儿血清总IgE水平无显著性差异(P>0.05)。②特应性皮炎患儿外周血EOS计数为(623.33±309.11)×106/L,较正常对照组儿童显著增高(P<0.05);其中轻度AD患儿与正常儿童无显著性差异(P>0.05);重度AD患儿较中度AD患儿显著升高(P<0.05)。结论:检测血清总IgE水平及外周血EOS对诊断特应性皮炎有重要意义。
Objective：To investigate the clinical significance of level of total serum IgE and peripheral blood Eosinophil count（EOS） in children with atopic dermatitis（AD）.Methods： Determination of total serum IgE levels and peripheral blood EOS of light,moderate and severe AD children patients and healthy children of the same age group（45 cases of AD and 45 cases of healthy children as control） in our hospital.Results： ① Total serum IgE level of children with AD was（1026.73±379.25）kU/L,drastically higher than the IgE level of control group（11.47±2.11）kU/L（P〈0.05）;among light,moderate and severe AD patient children,total serum IgE levels were not significantly different（P〉0.05）.②Peripheral blood EOS count was（623.33±309.11）×106/L in children with AD,significantly higher（P〈0.05） then control children group;EOS count in mild AD children and normal children were significantly different（P〉0.05）;in children with severe AD,EOS count was dramatically higher than that of children with moderate AD（P〈0.05）.Conclusion： Total Serum IgE level and peripheral blood Eosinophil count（EOS） are important parameters in diagnosis of Atopic dermatitis.
出处
《中国民康医学》
2010年第18期2315-2315,2357,共2页
Medical Journal of Chinese People’s Health
