摘要
感染性休克的发展与转归机制复杂,早期诊断和积极干预有助于改善患者的预后.近年的研究显示,感染性休克时肾上腺髓质素前体、心房尿钠肽前体、血管内皮素1前体和血管加压素前体等多种血管活性肽前体的血浆浓度明显增高,并与疾病严重程度呈正相关,且上述血管活性肽前体在血浆中半衰期较长,检测方法简便,是早期诊断感染性休克有价值的生物学指标.
There are numerous complex mechanisms contributing to the evolution of septic shock, and early diagnosis and intervention will improve the prognosis of patient with septic shock. Recently plasma concentrations of some bio-markers like pro-ADM,pro-ANP,pro-ET1 and copeptin are found increasing in patient with septic shock.The plasma concentrations of these bio-markers are positively related with the severity of infection.These bio-markers have long halflife and are easily assayed. They may be the new bio-markers for the early diagnosis of septic shock.
出处
《国际儿科学杂志》
2010年第5期452-454,共3页
International Journal of Pediatrics
