摘要
目的评价帕瑞昔布钠对人工全膝关节置换术后引起的中度到重度疼痛的治疗效果。方法选择45例施行单侧人工全膝关节置换术的患者,分别在术前2 h和术后3 d内使用帕瑞昔布钠进行镇痛。对患者的疼痛情况进行数字疼痛评分和镇痛满意度评价,并评估相关不良反应。结果患者的术后疼痛均得到缓解。39例为轻度疼痛,6例中度疼痛。主观满意度总体优良率达86.67%。无严重不良反应发生。结论使用帕瑞昔布钠对人工全膝关节置换术可产生较好的术后镇痛效果。
OBJECTIVE To evaluate the therapeutic effect of the parecoxib sodium on medium to severe pain after total knee arthroplasty.METHODS Forty-five patients with total knee arthroplasty were enrolled into this group who received parecoxib sodium for analgesia 2 h before and within 3 d after surgery.The numeric rating scales,subjective satisfaction and relative adverse reactions were assessed.RESULTS Pain was relieved in all of the patients.Slight pain were reported in 39 patients and medium pain occurred in 6 patients.The subjective satisfaction was up to 86.67%.No severe adverse reaction was observed in these patients.CONCLUSION Parecoxib sodium is a meaningful agent for analgesia after total knee arthroplasty.
出处
《中国药学杂志》
CAS
CSCD
北大核心
2010年第18期1434-1435,共2页
Chinese Pharmaceutical Journal
