摘要
目的:探讨血清癌胚抗原(CEA)、组织多肽抗原(TPA)及C反应蛋白(CRP)浓度在大肠癌手术前后的变化及意义。方法:检测64例健康体检者(对照组)及大肠癌患者术前88例与术后两周84例血清CEA、TPA及CRP含量,分析大肠癌组手术前与对照组之间的关系及术后两周与术前的比较。结果:术前大肠癌组中血清CEA、TPA及CRP浓度显著高于对照组(P<0.01),三项联合检测的阳性率高于单项检测的阳性率(P<0.05),且术后两周与术前测定值相比明显降低(P<005或P<0.01)。结论:CEA、TPA及CRP检测在大肠癌诊断方面有一定价值,其联合检测可提高诊断率,术后判断疗效和预后等方面有一定的指导意义。
Objective：To explore the clinical value of combined detection for serum CEA, TPA and CRP in patients with colorectal cancer. Methods： The levels of CEA,TPA and CRP of serum were detected in 64 cases of healthy adults and 88 cases of colorectal cancer, and 84 patients two weeks after operation were detected again. Results： The levels and positive rates of CEA, TPA and CRP in colorectal cancer were more higher than those in the control group, and positive rates of combined detection for 3 kinds of tumor markers was higher than single, the levels of 3 tumor markers in 84 cases with colorectal cancer decreased obviously two weeks after operation. Conclusion： The combined detection for tumor markers of CEA, TPA and CRP has important significance in early diagnosis, observation of therapeutic effects and prognosis for colorectal cancer after operation.
出处
《现代肿瘤医学》
CAS
2010年第9期1783-1784,共2页
Journal of Modern Oncology
基金
河南省科技攻关项目(编号:082102310120)
关键词
大肠癌
癌胚抗原
组织多肽抗原
C反应蛋白
colorectal cancer
carcinoembryonic antigen
tissue polypeptide antigen
C-reactive protein
