摘要
目的探讨超声造影对鉴别诊断甲状腺结节良恶性的价值。方法回顾性分析39个甲状腺结节的彩色多普勒血流显像及超声造影灌注过程,观察病灶周边及内部造影剂灌注强度,通过时间-强度曲线分析,比较病灶周边感兴趣区(ROI)峰值强度(PI)与达峰时刻病灶内部ROI相对应的造影剂灌注强度(II)的差异程度,计算两者差值△I及诊断良、恶性结节的△I分界值。结果甲状腺恶性结节造影增强模式多为弥漫性整体增强(94.12%),良性结节多为周边先于内部增强(86.36%),并以周边环状增强为主,内部轻微增强或始终无增强。初步界定△I>6.08 dB时,良性结节可能性大,敏感度为85.71%;△I<2.89 dB时,恶性结节可能性大,敏感度为82.35%。结论超声造影对鉴别甲状腺结节的良恶性有一定实用价值。
Objective To investigate the value of contrast-enhanced ultrasonography（CEUS） in the differential diagnosis of benign or malignant thyroid nodules.Methods Color Doppler flow imaging（CDFI） and contrast-enhanced ultrasonography perfusion of 39 thyroid nodules were retrospectively analyzed.The filling intensity of both periphery and interior of the nodule by the time-intensity curve（TIC） was observed.The evaluated parameters included peak intensity（PI） of the periphery,interior intensity（II） at the PI time,the difference of PI and I（△I）.Then the diagnostic cut-of points for thyroid benign or malignant thyroid nodules was calculated.Results Most of the malignant thyroid nodules were filled SonoVue pervasively（94.12%）.Most of the benign thyroid nodules showed early wash in of the periphery（86.36%）,and the majority showed ring enhancement at periphery,slight or none enhancement in interior.It was prone to benign nodule when △I〉6.08 dB,and the sensitivity was 85.71%.Simultaneously,it was prone to malignant nodule when △I〈2.89 dB and the sensitivity was 82.35%.Conclusion CEUS is valuable in the differential diagnosis of benign or malignant thyroid nodules.
出处
《中国医学影像技术》
CSCD
北大核心
2010年第8期1441-1443,共3页
Chinese Journal of Medical Imaging Technology
