摘要
目的:探讨近年来保济丸中化学与药理研究进展,为今后保济丸的深入研究提供一定的理论依据。方法:通过查阅近十年保济丸的相关著作与文献,从保济丸抑菌、抗炎、镇痛、止泻及对胃肠道功能具有双向调节等现代药理作用与其对应单味药、药对的主要化学成分的研究进行分析总结。结果:研究发现保济丸中抑菌、抗炎成分超过9种,镇痛与止泻及对胃肠道功能紊乱有调节作用的化学成分超过5种,复方中增强药理作用的药对共9对。结论:研究结果表明保济丸的现代药理作用与化学成分的研究与其传统中医临床疗效相对应,有利于保济丸的进一步开发与利用。
Objective：To review the research progress in Baoji pills’ chemical compositions and pharmacological effects in recent years,to provide bases for the future studies of Baoji pills.Method：By investigating references on Baoji pills in recent decades,the pharmacological effects of antibacterial,anti-inflammatory,analgesic,anti-diarrhea and on gastrointestinal functions of Baoji pills,the main chemical components of the single herb in the pills and the drug-pairs based on Baoji pills are summarized.Result：More than nine kind ingredients with antibacterial,anti-inflammatory effects are found the Baoji pills.More than five kinds of components which have a moderate effect of analgesic and anti-diarrhea,and for disorders of the gastrointestinal tract are also found.The drug-pairs with pharmacological enhancing effects in Baoji pills are nine pairs.Conclusion：The Baoji pills’pharmacological effects and chemical constituents corresponds its traditional clinical applications.The recent research progress in Baoji pills will benefit the further development and utilization of the pills.
出处
《中国实验方剂学杂志》
CAS
北大核心
2010年第11期200-203,共4页
Chinese Journal of Experimental Traditional Medical Formulae
基金
2008年粤港关键领域重点突破项目(TC08BE33-6)
关键词
保济丸
单味药
药对
化学成分
药理作用
Baoji pills
single herb
drug-pair
chemical component
pharmacological effect
