摘要
岩藻聚糖硫酸酯是一种硫酸多糖,具有多种生物活性.多糖化学修饰可提高多糖活性或使多糖产生新的活性.作者对岩藻聚糖硫酸酯衍生物的制备工艺和活性等进行了综述,包括低分子衍生物、脱硫衍生物、过硫酸化衍生物、乙酰化衍生物、苯酰化衍生物、磷酸化衍生物和氨基化衍生物等,以期促进岩藻聚糖硫酸酯的研究,获得高效、新型多糖药物.
Fucoidan is a kind of sulfated polysaccharide with a variety of biological activities.Chemical modification of polysaccharides can improve their bioactivities or make them produce new activities.In order to improve research of fucoidans and gain new polysaccharide drug with high bioactivity,this paper reviews preparative techniques and bioactivities of fucoidan derivatives,including low molecular weight fucoidan,desulfated fucoidan,oversulfated fucoidan,acetylated fucoidan,benzoylated fucoidan,phosphorylated fucoidan,aminated fucoidan and so on.
出处
《国际生物医学工程杂志》
CAS
北大核心
2010年第4期254-256,I0001,共4页
International Journal of Biomedical Engineering
