摘要
目的:探讨几丁质对运动小鼠糖代谢障碍的改善作用机制。方法通过游泳训练建立代谢糖障碍动物模型,测定小鼠血糖、肌糖原和肝糖原的含量。结果:在安静状态下,服药组小鼠肝糖原、肌糖原和血糖显著高于安静对照组(P<0.05);运动后即刻服药组和对照组比较,肝糖原和肌糖原显著升高(P<0.05);运动后24h恢复后服药组肝糖原、肌糖原和血糖恢复水平均显著高于其对照组(P<0.05)。训练服药组力竭游泳时间比训练对照组延长33.99%.结论:几丁质对改善运动所致机体糖代谢障碍具有良好的功效。
Objective ：To study the mechanism of chitosan on carbohydrate metabolism disorder in exercising mice.Methods：The animal model of carbohydrate metabolism disorder was established through swimming trainings and the content of blood glucose,muscle glycogen and liver glycogen in mice were all surveyed.Results ：When quiet,liver glycogen,muscle glycogen and blood glucose of drug-taking group were much higher than those of control group（P0.05）.Compared with control group,the liver glycogen and muscle glycogen of instant drug-taking group after exercises level to a higher degree（P0.05）.The renewing level of liver glycogen,muscle glycogen and blood glucose in drug-taking group after spending 24 hours on recovery was evidently higher than that of control-group（P0.05）.The exhaustive swimming time of drug-taking group was longer than that of exercise-control group by 33.99%.Conclusion ：Chitosan takes effect well in improving carbohydrate metabolism disorder resulting from exercises.
出处
《陕西医学杂志》
CAS
2010年第9期1124-1125,1141,共3页
Shaanxi Medical Journal
关键词
代谢疾病/药物疗法
氨基酸类
碱性/治疗应用
肝糖原/代谢
血糖/代谢
动物
实验
小鼠
Metabolic diseases/drug therapy Amino acids
basic/therapeutic use Liver glucogen/metabolism Blood glucose/metabolism Amimals
laboratory Mice
