摘要
目的探讨依达拉奉联合苦碟子对急性脑梗死患者凝血纤溶系统的影响。方法 92例急性脑梗死患者随机分为治疗组(依达拉奉注射液+苦碟子注射液)和对照组(苦碟子注射液),治疗前及治疗后测定血浆中D-二聚体(D-D)、纤维蛋白原(Fig)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)。结果对照组和治疗组的PT、APTT、Fig、D-D在治疗前无统计学意义(P>0.05),治疗后上述4项指标均较治疗前有统计学意义(P<0.05或P<0.01);治疗组和对照组相比,除PT外的其余3项指标间有统计学意义(P<0.05),治疗组治疗后APTT为35.44 s±2.37 s,Fig为3.25 g/L±0.37 g/L,D-D为583.1 ng/mL±103.5 ng/mL。结论依达拉奉联合应用苦碟子对急性脑梗死患者凝血纤溶系统有显著影响。
Objective To approach the effect of edaravone injection combined with Kudiezi injection on blood coagulation system and fibrinolytic system in patients（pts） with acute cerebral infarction（ACI）.Methods Ninety-two pts with ACI were randomly divided into two groups：Treatment group treated with edaravone injection and Kudiezi injection,and control group treated with Kudiezi injection.D-dimmers（D-Ds）,fibrinogens（Fig）,prothrombin time（PTs）,and activated partial thromboplastin time（APTTs） were determined pre-and post-treatment.Results There were no difference in D-Ds,Fig,PTs,and APTTs between two groups pre-treatment（P〈0.05）,and there were statistical difference post-treatment（P〈0.05 or P〈0.01） except PT.The APTT,Fig and D-D were 35.44 s±2.37 s,3.25 g/L±0.37 g/L and 583.1 ng/mL±103.5 ng/mL in treatment post-treatment.Conclusion Edaravone injection combined with Kudiezi injection had prominent effect on coagulation system and fibrinolytic system in pts with ACI.
出处
《中西医结合心脑血管病杂志》
2010年第9期1066-1067,共2页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
基金
2007年湛江市科技立项基金课题<依达拉奉联合苦碟子注射液治疗急性缺血性脑梗死的临床观察>(湛江市科技项目编号:2007C07022)
关键词
依达拉奉
苦碟子
急性脑梗死
凝血纤溶系统
edaravone injection
Kudiezi injection
acute cerebral infarction
coagulation and fibrinolytic system
