摘要
目的探讨化疗联合热疗治疗中晚期食管癌的临床疗效。方法 51例中晚期食管癌患者,治疗组26例采用奥沙利铂+氟脲嘧啶方案化疗联合热疗,对照组25例单用化疗,比较2组近期疗效及毒副反应。结果化疗联合热疗组有效率(61.5%)高于单纯化疗治疗中晚期食管癌有效率(48.0%),差异有统计学意义(P<0.05),恶心呕吐、白细胞减少发生率低于对照组(P<0.05)。结论化疗联合热疗对中晚期食管癌有协同治疗作用且毒副反应较小。
Objective Investigate efficacy of chemotherapy combined with hyperthermia in advanced esophageal carcinoma.Methods 51 patients with advanced esophageal cancer patients were enrolled in test group and 26 patients treated with oxaliplatin＋fluorouracil chemotherapy combined with hyperthermia,25 patients with advanced esophageal cancer patients were included in control group and treated with chemotherapy only,the efficacy and toxicity of 2 groups were compared.Results There are higher clinical treatment reponse and less toxicity in test group than that in control group（P0.05）.Conclusion Chemotherapy combined with hyperthermia on advanced esophageal cancer may have synergistic effect and less toxicity.
出处
《新疆医科大学学报》
CAS
2010年第6期701-702,共2页
Journal of Xinjiang Medical University
关键词
食管癌
奥沙利铂
氟脲嘧啶
热疗
esophageal cancer
oxaliplatin
fluorouracil
hyperthermia
