摘要
溃疡性结肠炎(ulcerative colitis,UC)的病因及发病机制目前尚不明确,但免疫异常已被公认是其发病的主要因素之一.近年,不少研究表明神经肽Y(neuropeptide Y,NPY)在免疫系统中起着重要作用.因此,推测NPY在UC的发生发展中可能也起着重要作用,本文就目前NPY与免疫和UC的研究现状作一简要评述.
The pathogenesis of ulcerative colitis (UC) remains unclear.Immune dysfunction has been considered to be main etiological factor for UC.Increasing evidence suggests that neuropeptide Y (NPY) is involved in immune dysfunction and the pathogenesis of UC.This paper reviews the latest advances in understanding the role of NPY in the immune system and the pathogenesis of UC.
出处
《世界华人消化杂志》
CAS
北大核心
2010年第19期2013-2016,共4页
World Chinese Journal of Digestology
基金
国家自然科学基金资助项目
No.30770983~~