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核素心肌灌注显像在肥厚型心肌病及高血压性心肌肥厚诊断中的应用研究 被引量:3

The clinical evaluation of myocardial perfusion imaging in patients with hypertrophic cardiomyopathy and hypertensive myocardial hypertrophy
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摘要 目的:探讨99Tcm-MIBI心肌灌注显像在肥厚型心肌病及高血压性心肌肥厚诊断中的应用价值。方法:确诊的肥厚型心肌病患者12例,其中间壁肥厚型10例,心尖部肥厚型2例,接受静态心肌灌注显像;临床确诊的向心性左室肥厚的高血压患者22例,接受运动负荷-静态心肌灌注显像。结果:①10例间壁肥厚型患者的间壁与后壁比值为1.8~2.7,平均为2.28,2例心尖部肥厚型患者的心尖与后壁比值分别为1.8、2.3,以间壁(心尖)与后壁比值大于1.3为诊断标准,诊断灵敏度为100%;超声心动图首次诊断灵敏度为83.3%(10/12)。②两组患者核素心肌灌注显像计算的间壁(心尖)与后壁比值分别为(2.24±0.29)和(1.19±0.16),组间比较有显著性差异(P〈0.01);两组患者超声计算比值分别为(2.02±0.33)和(1.15±0.11),两种检查结果间相关性良好,相关系数r为0.96。③肥厚型心肌病组核素心肌灌注显像共检出合并心肌缺血7例,以冠脉造影为对照,心肌灌注显像的灵敏度为100%、特异性为50%;高血压性心肌肥厚组共检出心肌缺血9例,灵敏度为80.0%、特异性为91.7%。结论:核素心肌灌注显像可准确诊断及鉴别肥厚型心肌病及高血压性心肌肥厚,并能同时检测心肌缺血,但对于肥厚型心肌病应注意假阳性的问题。
出处 《中国临床医学影像杂志》 CAS 北大核心 2010年第8期581-583,共3页 Journal of China Clinic Medical Imaging
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参考文献4

  • 1Lazzeroni E,Rolli A,Aurier E,et al.Clinical significance of coronary artery disease in hypertrophic cardiomyopathy[J].Am J Cardiol,1992,70(4):499-501. 被引量:1
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二级参考文献7

  • 1Lazzeroni E,Rolli A,Aurier E,et al.Clinical significance of coronary artery disease in hypertrophic cardiomyopathy.J Am J Cardiol,1992,70:499-501. 被引量:1
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  • 7O′Gran PT,Bonow RO,Maron BJ,et al.Myocardial perfusion abnormalitites in patients with hypertrophic cardiomyopathy:Assessment with thalium 201 emission computed tomography.Circulation,1987,76:1214-1223. 被引量:1

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