摘要
目的 比较０．７５％ 罗哌卡因和０．５％ 布比卡因对剖宫产手术硬膜外麻醉的临床效果，为罗哌卡因临床应用提供客观依据。方法 ２０ 例剖宫产术患者（ＡＳＡⅠ～Ⅱ级）随机分为二组，Ⅰ组：０．７５％ 罗哌卡因（ｎ＝ １０ 例）；Ⅱ组：０．５％ 布比卡因（ｎ＝ １０ 例）。取Ｌ２～３ 行硬膜外穿刺，向上置管３ｃｍ ，注入１．０％ 利多卡因５ｍ ｌ试验量，５ 分钟后注入首次剂量罗哌卡因或布比卡因８～１５ｍ ｌ，总量不超过２０ｍ ｌ。结果 两组病人用药总量、感觉阻滞范围和起效时间无明显差异。Ⅰ组感觉运动阻滞分离较明显，止痛和肌松效果良好，对血压和心率影响小。结论 与０．５％ 布比卡因相比，０．７５％ 罗哌卡因感觉阻滞完善，感觉和运动阻滞分离明显，止痛和肌松效果良好，对循环功能影响小，不良反应发生率低。
Objective To investigate the effects of 0 75% Ropivacaine compared with 0 5% Bupivacaine for epidural anesthesia in Caesarean Section in order to provide basis of the clinical application of Ropivacaine Method 20 parturients (ASA Ⅰ～Ⅱ) were divided into two groups randomly Group 1:0 75% Ropivacain (n=10),group Ⅱ:0 5% Bupivacaine (n=10) In all patients epidural space L 2～3 was selected ,then the catheter was put upward 3cm 1% Lidocaine 5ml as a test dose and five minutes later,the initial dose of Ropivacaine/Bupivacaine 8～15ml were injected The total dose of the study drugs were less than 20ml Results There were no significant difference of total dose,level and onset time of sensory block between two groups But in group Ⅰ: sensory motor differentiation was more obvious,more satisfactory analgesia and muscle relaxation were obtained with less changes of blood pressure and heart rate Conclusion Compared with 0 5% Bupivacaine,0 75% Ropivacaine provides more satisfactory sensory block,sensory motor block differentiation anesthesia and muscle relaxation with less effect on cardiovascular function and fewer adverse events
出处
《中华麻醉学杂志》
CAS
CSCD
北大核心
1999年第5期276-278,共3页
Chinese Journal of Anesthesiology
关键词
布比卡因
罗哌卡因
硬膜外阻滞
剖腹产
Bupivacaine Ropivacaine Anaesthesia,epidural Cesarean section Seensory and motor block
