摘要
目的探讨ＡｇＮＯＲ和肥大细胞与大肠癌诊断及分级的关系。方法对４４例大肠癌，１２例大肠腺瘤，１６例癌旁粘膜做ＡｇＮＯＲ计数及肥大细胞计数。结果ＡｇＮＯＲ和肥大细胞计数在大肠腺瘤及腺癌间差异有显著性（Ｐ＜０．０１），ＡｇＮＯＲ计数随大肠腺癌分化程度的降低而增多，两者呈负相关。肥大细胞计数随大肠癌分化程度的降低而降低，两者呈正相关。结论ＡｇＮＯＲ和肥大细胞计数对大肠癌诊断。
Objective To study the relationship between argyrophilic
nucleolar organizer region associated protein(AgNOR),mast cell and colorectal cancer.Method
Mast cells and AgNOR were counted in 44 cases of colorectal cancer,16 cases of colorectal
adenoma,12 cases of normal mucosa.Result The granule number of AgNOR and the number of
mast cells from colorectal cancer were significant different to colorectal adenoma(P<0.01).The
granular numbers of AgNOR were increased with the decreasing degree of histological
differentiation of colorectal cancer.AgNOR is inverse correlation to histological
differentiation.The number of mast cell was decreased with the decreasing degree of
histological differentiation.Conclusion The AgNOR and mast cell quantitative analysis might be
useful in diagnosis and judging prognosis of colorectal cancer.
出处
《潍坊医学院学报》
1999年第1期5-6,共2页
Acta Academiae Medicinae Weifang
