摘要
目的探讨甲型H1N1流感主要的临床表现,分析早期症状与发生重症流感的相关性。方法回顾性分析2009年5—10月我院确诊的甲型H1N1流感住院病例187例,符合重症标准的30例(胸部X线片提示肺炎),157例普通型,不包括危重症病例。结果 187例患者的平均年龄为(20.61±13.87)岁;男女比例98:89。最常见的症状和体征为发热(90.9%)和咳嗽(78.6%)以及咽部充血(80.2%)和扁桃体肿大(65.2%)。所有患者的症状体征均于15d内消失,平均(5.01±2.39)d。发热持续时间平均(3.56±1.96)d。甲型H1N1流感病毒核酸阳性持续时间平均(5.51±2.29)d。肺炎发生独立危险因素包括出现气促、症状持续时间超过7d。结论甲型H1N1流感临床症状类似季节性流感,多数病例为自限性、轻症病例,出现气促并且症状持续超过7d提示可能为重症病例。
Objective To investigate the major clinical manifestations of influenza A （H1N1） and to analyze the correlation of the early symptoms to occurrence of severe influenza A （H1N1）.Methods The data of 187 inpatients of our hospital during May and October 2009 were retrospectively analyzed,Among them 30 patients met the standards of severe condition （chest X-ray revealed pneumonia）,157 met the standards of general condition,and no one met the standards of critical condition.Results The mean age of the 187 patients was （20.61±13.87） years,and the male to female ratio was 98：89.The most common symptoms were fever （90.9%） and cough （78.6%）,and the most common signs were pharyngeal hyperemia （80.2%） and tonsil swelling （65.2%）.The signs and symptoms of all the patients disappeared within 15 days,with an average of （5.01± 2.39） days.Average duration of fever was （3.56±1.96） days.The median length of time during which patients had positive real-time RT-PCR test results of influenza A （H1N1） virus nucleic acid was （5.51±2.29） days.Independent risk factors for the incidence of pneumonia included shortness of breath,and symptom duration of more than 7 days.Conclusion The symptoms of influenza A （H1N1） are similar to seasonal influenza,and the majority were of self-limiting and mild condition.The shortness of breath and duration of symptoms more than seven days may prompt a severe case.
出处
《中国全科医学》
CAS
CSCD
北大核心
2010年第25期2837-2838,2841,共3页
Chinese General Practice
关键词
甲型H1N1流感
肺炎
呼吸衰竭
Influenza A H1N1 influenza
Pneumonia
Respiratory failure
