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重症肺炎患者外周血自然杀伤细胞变化的意义 被引量:3

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摘要 目的观察重症肺炎患者外周血中自然杀伤细胞的变化,探讨其在评估重症肺炎的病情及预后中的意义。方法采用流式细胞仪检测轻症肺炎40例和重症肺炎56例的外周血自然杀伤细胞占淋巴细胞比例的变化。结果轻、重症肺炎患者的NK细胞绝对数及比值与对照组相比均降低,均有显著性差异(P<0.01),轻、重症肺炎两组相比,有显著性差异(P<0.01);MODS组NK细胞绝对值及比值明显低于非MODS组,有显著性差异(P<0.01);死亡患者的NK细胞绝对值及比值明显低于存活组,两者有显著性差异(P<0.05)。结论检测外周血NK细胞绝对数及其占淋巴细胞的比例对评估重症肺炎的病情和预后有重要的临床意义。
作者 李金美
机构地区 丽水市人民医院
出处 《浙江实用医学》 2010年第4期266-267,共2页 Zhejiang Practical Medicine
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