摘要
目的:了解牙周炎患者龈下菌斑细菌对于口腔常用抗菌药物的敏感性。方法:从慢性牙周炎患者龈下菌斑中分离培养牙周可疑致病菌,测定6种口腔常用抗菌药物对其的最低抑菌浓度,分析以上致病菌对这几类抗菌药物的敏感性。结果:共从50名慢性牙周炎患者牙周袋中分离培养72株革兰阴性厌氧菌进行药物敏感试验。全部实验菌株都对阿莫西林/克拉维酸敏感。对甲硝唑、替硝唑、奥硝唑未见耐药株产生。结论:对于慢性牙周炎患者龈下菌斑中分离的厌氧菌,阿莫西林/克拉维酸和硝基咪唑类药物甲硝唑、替硝唑和奥硝唑的抑菌作用强。
Objective：To evaluate the antimicrobial susceptibility of subgingival microorganisms from the patients with chronic periodontitis.Methods：The putative periodontal pathogens were isolated from subgingival plaque inthe patients with chronic periodontitis.The antimicrobial susceptibility to 6antimicrobial agents were studied and the minimum inhibitory concentrations were measured.Results：72 isolates from subgingival plaque samples from 50 patients were obtained.All the tested strains were susceptible to amoxi-cillin/clavulanic acid.No resistant strains to metronidazole, tinidazole and ornidazole were found.Conclusion：The amoxicillin/clavulanic acid, metronidazole, tinidazole and ornidazole have an excellent antimicrobial activity to the isolated periodontal pathogens in patients with chronic periodontitis.
出处
《现代生物医学进展》
CAS
2010年第15期2926-2928,共3页
Progress in Modern Biomedicine
关键词
牙周可疑致病菌
抗菌药物
Chronic periodontitis
Subgingival plaque
