摘要
目的 观察吉非替尼联合GP方案（吉西他滨＋顺铂）一线治疗晚期肺腺癌的临床护理方法和特点.方法 回顾性分析43例初治ⅢB、Ⅳ期肺腺癌患者临床护理资料.结果 实验组与对照组毒副反应发生率分别为骨髓毒性（34.8%,40.0%）、恶心、呕吐（78.3%,75.0%）及腹泻（21.7%,5.0%）,差异无统计学意义（P〉0.05）.皮疹或痤疮（26.1%,0%）发生率差异有统计学意义（P〈0.05）.结论 严密的病情观察和有效的护理措施,能有效提高患者的生活质量,帮助患者尽早康复.
Objective To evaluate characteristics of clinical nursing for advanced lung adenocarcinoma treated with gefltinib combined with GP program （gemcitabine, cisplatin） as the first-line proposal. Methods To analyze the nursing data of 43 patients who were diagnosed as phase Ⅲ B, IV adenocarcinoma lung cancer in August 2008 ～ December 2009 in our department retrospectively. Results The incidence rate of bone marrow toxicity in experimental group and control group was 34. 8% and 40. 0% respectively , The rate of nausea, vomiting was 78.3% and 75.0% and diarrhea was 21.7% and 5.0% , there was no significant difference （P 〉 0.05）. The incidence rate of Rash or acne was 26.1% and 0, the difference had statistical significance （x2 = 6.06,P =0.01）. Conclusions The strict observation and effective care measures can improve the quality of life of patients and help patients to rehabilitate as soon as possible.
出处
《中华现代护理杂志》
2010年第22期2630-2632,共3页
Chinese Journal of Modern Nursing
关键词
肺肿瘤
药物疗法
联合
护理
靶向治疗
吉非替尼
Lung cancer
Chemotherapy, Combination
Nursing
Targeted therapy
Cefitinib
