摘要
目的：观察缺血性脑卒中后癫痫发作病人脑电图（EEG）的动态改变。方法：对40例缺血性脑卒中后癫痫发作病人（观察组）和20例缺血性脑卒中后无癫痫发作病人（病例对照组）的EEG和卒中病灶分布、范围、美国国立卫生研究院卒中量表（NIHSS）评分、癫痫发作形式及频数进行分析比较。结果：观察组40例的病灶分布主要在颞叶、额叶及顶叶，初次NIHSS评分为4．8（±2．03）分，癫痫发作类型主要为全面性强直阵挛发作；病例对照组20例的病灶分布在顶、枕、额、颞叶、基底节和小脑，初次NIHSS评分为4．7（±2．27）分，经t检验统计表明，NIHSS评分两者差异无显著意义（P〉0．50）；初次检查病例对照组的EEG异常率为50％，其中轻度异常占异常总数的70％，中度占30％；观察组的EEG异常率为95％，其中轻度异常仅占异常总数的21％，中度和重度异常占79％；健康对照组的EEG异常率很低，仅为20％，且仅表现为轻度异常；经Х^2检验，Х^2=46．54，P〈0．005，表明三组间EEG的异常率差异有显著意义。在随后的3次复查中，随着NIHSS评分的改善，癫痫发作的频数降低，EEG的异常程度也下降，以第60天时最为显著。结论：缺血性脑卒中后癫痫发作病人的EEG检查有较高的异常率，对指导其临床治疗和判断预后具有一定的价值。
Objective：To observe the dynamic changes of electroencephalogram （ AEEG）in patients with epileptic attack after ischemic stroke. Methods： To analyze the distribution of stroke zone,National Institutes of Health Stroke Scale （NIHSS） scoring, types and frequency of epileptic seizure in 40 patients with epileptic seizures after iscbemic stroke（the Observed Group） and 20 patients with ischemic stroke without epileptic seizure（the Control Group）. Results.. The distribution of stroke lesions foci in the Ob- served Group were on the temporal , frontal and parietal lobe,the scoring of the preliminary NIHSS was 4.8±2.03. The main type of epileptic seizures was generalized seizures. The distribution of stroke lesions loci in the Control Group were on the parietal, occipital, frontal, temporal 10be and basic gangenlia and cerebellem , and the scoring of preliminary NIHSS was 4. 7 ± 2. 27. With statistic analysis from tests, the results ：showed the deference between the two groups of the scoring of NIHSS had no significant difference（P〉0.50）. The abnormality rate of preliminary EEG in the Control Group was 50 %, and the mild abnormality accoant for 70% of the total number of abnormalities, and middle abnormality account for 30%. The abnormallity rate of EEG in the Observed Group was 95%, and the mild abnormality only account for 21% of the totality number of abnormalities, and middle and severe abnormality account for 79%. The abnormality rate of EEG in the Control Group was very low, as 20%, and only showed mild abnormality. With statistic analysis from Chi-square test, the results showed .Х^2= 46.54,P 〈0. 005, and the abnormality rate of EEG among the 3 groups had significant difference. In the following 3 examinations, with the improvement of NIHSS scoring, the frequency of epileptic attack gradually decreased, and the abnormaliyt rate of EEG also decreased, and the climax of it was on the 60t~ days. Conclusion： Ambulatory EEG could enhance the abnormality rate of EEG examination in pati
出处
《癫痫与神经电生理学杂志》
2010年第4期213-216,共4页
Journal of Epileptology and Electroneurophysiology(China)
基金
深圳市科技局资助课题（项目编号：TH200505270435B）
