摘要
目的了解ＴＴ病毒（简称ＴＴＶ）在血液透析患者和骨髓移植患者中的感染情况，并评估ＴＴ病毒的致病力。方法回顾性调查３７例血液透析患者和９０例骨髓移植患者的ＴＴＶ感染情况，分析ＴＴＶ感染的致病力。结果ＴＴＶ在３７例血液透析患者中的感染率为１６２２％（６／３７），在９０例骨髓移植患者中的感染率为３３３％（３／９０），经统计学处理，两组感染率比较有显著性差异。６例ＴＴＶ阳性患者中５例有输血史，４例行肾移植术。ＴＴＶ感染与是否存在ＨＢＶ或ＨＣＶ感染无关。未发现ＴＴＶ阳性和ＴＴＶ阴性两组之间肝功能的损害程度存在差异。结论输血或血浆在传播ＴＴＶ感染上有重要意义。ＴＴＶ的致病力较弱。ＴＴＶ是否嗜肝病毒，有待进一步研究。
Objective To make clear the infection of TT virus(TTV) in patients of hemodialysis and bone marrowtransplantation and to evaluate the virulence. Methods The TTV infection were investigated in 37 cases of hemodialysis and 90 cases of bone marrowtransplantation by means of review method. Results The positive rate of TTV was 16.22%(6/37) in 37 cases of hemodialysis and 3.33%(3/90) in 90 cases of bone marrowtransplantation. The difference between them was significant(P<0.01). Of the six TTVpositive patients, 5 had blood transfusion and 4 of them had bone marrowtransplantation. Infection of TTV had nothing to do with the infection of HBV and HCV. There were no significant differences in the results of liver function tests between TTV positive and TTV negative patients. Conclusion These results suggest that blood transfusion might be one of the critical routes to transmit TTV. The virulence of TTV might be mild. Whether TTV is a hepatitis viral remains further study.
出处
《中华实验和临床病毒学杂志》
CAS
CSCD
1999年第2期194-196,共3页
Chinese Journal of Experimental and Clinical Virology
基金
广东省自然科学基金
