摘要
季节性流感疫苗对健康人群有明显的保护作用,具有良好的安全性,接种流感疫苗是流感预防最有效的方法。由于非健康人群自身的免疫功能与健康人群有差异,加之非健康人群在治疗过程中使用的药物导致的免疫妥协现象,非健康人群接种季节性流感疫苗后的有效性和安全性问题日益受到广泛关注。本文拟对包括实体癌患者、器官移植受体患者、进行免疫调节和英夫利昔单抗治疗的炎性肠病(IBD)儿童患者等在内的非健康人群使用季节性流感疫苗后的有效性和安全性的最新研究进展做一综述,为上述类型患者临床上合理使用季节性流感疫苗预防流感提供科学依据。
Seasonal influenza vaccine performs perfect safety and efficacy to healthy population.Inoculating is the best way to prevent seasonal influenza.Because of the difference of immune function between healthy population and patients,and immunocompromise in patients evoked by medication during therapy,the safety and efficacy of the seasonal influenza vaccine when used in patients caused worldwide concern.The article will review the study progress on safety and efficacy of the seasonal influenza vaccine when inoculated in sufferers including patients with solid cancer,organ transplant recipients,inflammatory bowel disease patients receiving infliximab and immunomodulatory therapy,to provide scientific basis for the reasonable administration of seasonal influenza vaccine in the patients mentioned above.
出处
《中国国境卫生检疫杂志》
CAS
2010年第4期279-282,共4页
Chinese Journal of Frontier Health and Quarantine
