摘要
本文对52例各类手术患者的甲状腺功能作了动态观察,小手术组手术前后各项指标均无明显变化,择期组及重危组术后血清L_3、FT_3显著降低(P<0.01);rT_3明显升高(P<0.01)。择期组术后7天各指标恢复到术前水平,而重危组术后14天方恢复到术前水平。术后T_3/rT_3比值<0.5者,重危组(78.6％)明显高于择期组(32.1％,P<0.01)。特重患者T_4也明显低于正常值。死亡前FT_3及rT_3显著降低。提示术后甲状腺功能的变化及其恢复快慢与病情及手术大小有关。病情越重,手术范围越大,恢复越慢。对手术患者进行甲状腺功能动态观察,可作为判断病情轻重,估计预后的一个辅助指标。
Thyroid function was observed in 52 patients before and after operation. After minor surgery the changes in levels of serum thyroid hormones were not evident. In both selective operation and critical patient groups, serum T3 and FT3 levels decreased and rT3 increased after operation. These levels returned to normal within 7 days postoperatively in selective operation group and within 14 days in critical patient group. The postoperative T3/rT3 ratio was less than 0.5 in 78.6% (11/14) of critical patient and 32.1% (9/28) of selective operation cases. Serum T4 decreased obviously in 2 of 3 fatal cases, while serum FT3 and rT3 concentration decreased dramatically before they died. The postoperative changes in levels of hormones correlated with patients' condition and operation catagory. Hence repeated assessment of thyroid hormones in postoperative period may serve as an adjunctive prognostic parameter.
出处
《上海医学》
CAS
CSCD
北大核心
1990年第3期137-140,共4页
Shanghai Medical Journal
