摘要
目的:研究奥拉西坦的合成工艺。方法:以4-氯代-3-羟基丁酸乙酯、甘酰胺盐酸盐为原料合成奥拉西坦。考察反应时间、反应温度、催化剂用量、反应物料配比等因素对收率的影响。结果:在此适宜反应条件下的收率可达48.9%。结论:工艺条件较好。
Objective： To study the synthesis of oxiracetam.Method： Oxiracetam was synthesized by ethyl-4-chloro-3-hydroxybutyrate and Glycinamide hydrochloride.Molar ratio of raw materials,reaction time,reaction temperature and catalytic quantity were investigated.Results： Under the best conditions its yield was 48.9%.Conclusions： Better technique condition was acquired.
出处
《四川生理科学杂志》
2010年第3期108-110,共3页
Sichuan Journal of Physiological Sciences
