摘要
目的探讨氟硒及其联合作用对大鼠精子及睾丸形态学的影响。方法采用饮水加硒（３ｍｇ／Ｌ）和食物摄氟（５０ｍｇ／ｋｇ）的方法。结果加氟可使大鼠精子总数减少、存活率降低及睾丸生精过程受到轻度抑制，曲细精管管径变小等病理形态学改变。当硒氟共同作用时，上述变化均有不同程度的减轻。结论此剂量条件下的硒可拮抗慢性氟中毒所引起的生殖系统的变化。
Objective To study the combined
effects of fluoride and selenium on the morphological changes of sperm and testis. Methods\
Selenium (3 mg/L, in drinking water) and fluoride (50 mg/kg, in food) were administered to rats
for 3 months. Results\ Fluoride could reduce the sperm count and survival rate, inhibit the
spermatogenic process slightly. In addition, the diameter of convoluted seminiferous tubules
became thin by means of morphological method. In the rats administered by both fluoride and
selenium, the abovementioned effects appeared to be alleviated. Conclusion\ A certain dose of
selenium could antagonize the changes in rats' reproductive system caused by chronic fluoride
poisoning.
出处
《中国职业医学》
CAS
1999年第3期19-20,共2页
China Occupational Medicine
关键词
氟
硒
联合作用
精子
睾丸形态
fluoride, selenium, combined effects, sperm, testis
