摘要
气道压力释放通气是以持续气道正压为工作基础的压力控制机械通气模式,其从高气道压向低气道压释放压力产生通气量进行气体交换.它能在肺保护通气策略基础上维持肺复张、开放及减少呼吸机相关肺损伤.它对急性肺损伤/急性呼吸窘迫综合征患者在降低气道峰压及平均压、提高氧合、改善血流动力学和胃肠灌注、减少镇静和麻醉药物使用等方面产生广泛有利影响;而且,自主呼吸对重力依赖区塌陷肺组织的重新开放在其中发挥重要作用,其应用受到研究者和临床医师越来越多的关注.
Airway pressure release ventilation （APRV） is pressure controlled mechanical ventilation on the base of continuous positive airway pressure,and accomplishs ventilatory capacity for gas exchange by releasing pressure from high airway pressure to low airway pressure. It can sustain lung recruitment and reduce ventilator associated lung injury on the base of lung protective ventilatory strategies. APRV has many advantageous influence in decreasing airway pressures, improving oxygenation,improvements in hemodynamics and gastrointestinal perfusion, reducing sedation/anesthetics requirements in ventilatory support in the presence of acute lung injury/acute respiratory distress syndrome. Moreover, spontaneous breathing plays an important role in recruiting dependent collapsed lung regions throughout the entire ventilatory cycle. So,researchers and doctors pay more and more attention to APRV.
出处
《国际呼吸杂志》
2010年第15期939-943,共5页
International Journal of Respiration
基金
广东省医学科研基金资助（A2005685）
关键词
机械通气
气道压力释放通气
急性肺损伤
急性呼吸窘迫综合征
自主呼吸
治疗
Mechanical ventilation
Airway pressure release ventilation
Acute lung injury
Acute respiratory distress syndrome
Spontaneous breathing
Treatment
