摘要
目的研究多发性骨髓瘤（MM）患者血清内增殖诱导配体（APRIL）蛋白水平，并分析肿瘤坏死因子α（TNPα）的台量，且与临床治疗发病与预后的意义。方法应用酶联免疫吸附试验（ELISA）法，检测37例MM患者血清APRIL水平与肿瘤坏死因子，（TNFα）的含量，并与25例健康志愿者作了对照。结果MM患者血清APRIL和慨水平明显低于健康对照纽（P〈0．01）呈负相关。结论MM患者血清APRIL水干和TNFα与对照组存在着显著的差异，提示APRIL及TNFQ检测水平与MM患者发病及预后有关。
Objective To explore the APRIL protein level in serum of multiple myeloma（MM）patlents and analyze the content of TNF-α and the significance of clinical treatment morbidity and prognosis. Methods Apply ELISA method to detect serum APRIL level and content of TNF a of 37 NU patients and make comparison with 25 healthy volunteers. Result The serum APRIL and TNF α levels are significantly lower than the healthy control group（ p 〈 0.01 ） and shows negative correlation. Conclusion Serum APRIL and TNF α levels of MM patients have significant difference with control group and it suggests that APRIL and TNF a detecting levels relates with morbidity and prognosis of UU patlente.
出处
《医学检验与临床》
2010年第3期73-74,共2页
Medical Laboratory Science and Clinics
