摘要
目的对边缘性脑炎患者磁共振(MR)影像学表现进行探讨,以明确急性边缘性脑炎的特异性磁共振影像学征象,了解磁共振成像(MRI)在急性边缘性脑炎患者诊断以及病情评价中的应用价值。方法通过对2008年12月2010年1月间临床收集的8例边缘性脑炎患者进行MRI检查,并回顾性分析不同序列磁共振影像学表现,总结MRI征象,评价MRI检查在急性边缘性脑炎的临床诊治中的作用。结果边缘性脑炎患者显示特异性的双侧边缘系统肿胀及信号异常,呈T1WI低信号影;T2WI及FLAIR成像为高信号影像;增强扫描未见确切异常强化;FLAIR成像是检测病变最敏感的序列。部分患者可见累及边缘系统外结构。随访病例影像学改变可有明显好转。结论边缘性脑炎特异性损伤边缘系统,以双侧海马为主,MRI影像可直观反映边缘性脑炎早期及随访期改变,能直接了解边缘性脑炎颅内受累范围、程度及治疗后恢复情况等,可为其临床及时诊断及治疗评估提供有利信息。
Objective To evaluate the application of magnetic resonance imaging (MRI) and its manifestations in limbic encephalitis. Methods MRI (Signa 3.0T,GE) of 8 patients with acute limbic encephalitis (age range:25-53 years,male/female:4/3) were analyzed from December 2008 to January 2010. MRI signs were collected and evaluated for making the diagnosis of limbic encephalitis,and MRI's clinic application and values for the disease were summarized. Results Specific signs were observed in MR images,swelling and abnormal signals showed in bilateral limbic structures,hyper intense signals in FLAIR sequence was the most sensitive sign to detect the lesion. In some cases,structures outside the limbic system were also involved. Conclusion Limbic encephalitis specifically damages limbic system,such as bilateral hippocampus. MRI is the key method for the diagnosis and guidance of treatment of limbic encephalitis.
出处
《华西医学》
CAS
2010年第6期1105-1107,共3页
West China Medical Journal
关键词
边缘性脑炎
磁共振成像
Limbic encephalitis
Magnetic resonance imaging