摘要
目的：探讨原发性纵隔肿瘤的临床特点、诊治方法。方法：回顾分析我院1969年1月～1997年12月收治并经病理证实的407例原发性纵隔肿瘤。结果：胸腺瘤184例（45．2％），畸胎瘤99例（24．3％），神经源性肿瘤70例（1．2％），其它54例（1．3％）；除无手术指征的17例使用放、化疗外，手术探查390例，其中肿瘤完整切除352例，姑息性切除18例，手术切除率94．9％（370／390），探查20例；术后随诊1个月至28年，良性纵隔肿瘤未见复发。恶性胸腺瘤54例中，一年生存率88．8％（48／54），3年64．8％（35／54），5年57．4％（31／54），10年46．3％（25／54）。恶性畸胎瘤14例中，1年生存率50％（7／14），3年28．6％（4／14），5年14．3％（2／14）。结论：本病诊断主要依靠临床症状和X线、CT检查；治疗应以手术为主；对巨大的或手术较困难的纵隔肿瘤的手术治疗应做好充分准备；手术进路视肿瘤的大小和部位而定。
Objective: To Evaluate the clinical characteristics, diagnosis and treatment in primary mediastinal tumors (PMT). Methods: From January 1969 to December 1997, 407 cases of pathologically confirmed PMT were treated at our hospital. They were analyzed. Result: Among 407 cases, there were 184 thymomas (45. 2% ), 99 teratoblastomas (24. 3% ), 70 neurofihromas (17. 2% ) and 54 others (13. 3% ). Except 17 cases can not be operated, all other cases were treated with chemotherapy and radiotherapy Exploratory surgery was performed in 390 cases. Among them radical excision in 352 (90. 3% ), palliative excision in 18 (4. 6% ), exploratory thoractotomy in 20(5.1% ), No replase was reported in benign PMT patients who had received radical excision during the followup period of I month to 28 years. Malignant thymoma 54 cases, the 1、3、5 and 10-year survival rates were 88. 8% (48/54) .64. 8% (35/54) .57. 4% (31 /54) and 46. 3% (25/54) respectively. In malignant teratoblastomas (14 cases), the 1、3 and 5-year survival rates were 50% (7/ 14) 28. 6% (4/14) and 14. 3% (2/ 14) respectively. Conclusion: Besides clinical symptoms and X-ray examinations Of the chest, CT scan have great valule in the diagnosis and differential diagnosis of PMT. The main treatment of PMT is surgical. For giant mediastinal tumors, preoperative evalution should be comprehensive, attentions during the operation should he considered. The choice of incisions were discussed in the paper.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1999年第1期79-81,共3页
Chinese Journal of Cancer
关键词
纵隔肿瘤
诊断
外科手术
Mediastinal neoplas mas/diagnosis
Mediastinal neoplasmas/surgery
