摘要
目的：探讨外科治疗复发性喉癌的方法和预后。方法：1970－1990年间手术治疗44例复发性喉癌，其中局部复发25例，全喉切除22例，半喉切除1例，喉、颈段食管广泛切除加前臂双皮岛游离皮瓣修复1例，手术探查1例；19例颈淋巴结转移，全部行根治性颈淋巴结清扫术。本组病例均随访5年以上。结果：总的3、5年生存率分别为47．74％和39．78％。其中局部复发组、颈淋巴结转移组的5年生存率分别为55．71％和14．86％。结论：复发性喉癌的治疗应以外科治疗为主；颈淋巴结转移是影响喉癌预后的重要因素，提示对T3、T4期病例行预防性颈淋巴结清扫对改善预后有意义。
Objective: To evaluate the effectiveness of surgery in the treatment of recurrent laryngeal carcinoma, and to investigate the prognostic factors of recurrent laryngeal carcinoma. Methods: From 1970 to 1990, 44 cases of recurrent laryngeal carcinoma had deen treated by surgery. 25 cases were recurrent locally. Among them, 22 cases accepted total laryngectomy, one hemilaryngectomy and one wide incision and repairment with double free skin island flaps of forearm. Only one case was treated with operative exploration only.19 cases had lymph nodal metastases in the neck. All the cases received radical neck dissection. Follow-up of all patients was performed untill the time of death or over 5 years. Results: The 5-year survival rate was 55. 71% in the local recurrent group, while it was only 14. 86% in the cervical lymph node metastases group (P<0.05). The overall survival rates at 3 and 5 years were 47. 74% and 39. 78%, respectively.Conclusion: Surgical treatment is the mainstay for recurrent laryngeal carcinoma. The cervical lymph node metastasis is an important factors influencing prognosis of the laryngeal carcinoma. The elective neck dissection is important to improve the prognosis in staging Ⅲ and staging Ⅳ cases of the supraglottic carcinoma.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1999年第1期59-60,76,共3页
Chinese Journal of Cancer
关键词
喉肿瘤
外科手术
复发
Laryngeal neoplasma/surgery
Recurrent tumor
Laryngectomy
