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肿瘤的基因治疗:重新燃起的希望 被引量:5

Cancer gene therapy:a rekindled hope
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摘要 近年来,基因治疗取得了令人瞩目的进步,世界顶级权威杂志《Science》评出的2009十大科学突破,其中位列第七的就是基因治疗,这为我们征服肿瘤以及其他遗传性疾病带来了新的希望。本文拟从基因治疗发展历程的角度,以大量例证演绎基因治疗的辉煌与跌宕,归纳肿瘤基因治疗的成就与障碍,展望肿瘤基因治疗的发展和应用前景。 Gene therapy acquired a great achievement recently. The world's top magazine, Science, appraised 10 breakthroughs of the Year 2009, in which the seventh was gene therapy. It brings us a rekindled hope for overcoming the genetic diseases including cancer. In this review, we followed the development course of gene therapy, exhibited its resplendence and frustration with a great deal of exemplifications, then concluded the advantages and obstacles of cancer gene therapy. We also figured the potential prospects of gene therapy in cancer treatment.
作者 苏长青
出处 《临床肿瘤学杂志》 CAS 2010年第7期577-583,共7页 Chinese Clinical Oncology
基金 国家科技重大专项课题-重大新药创制资助项目(2009ZX09102-235)
关键词 肿瘤 基因治疗 载体 Cancer Gene therapy Vector
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